Knowledge Base

Scientific articles

Effect of maternal antibiotics on breast feeding infants

J. Mathew, Postgraduate Medical Journal (2004)
Abstract: Antibiotic usage is fairly common among breastfeeding mothers and there is potential for transfer to infants through breast milk. While most medicines taken by lactating women cause no harm to their babies, at times it can result in serious consequences. This article reviews the principles governing transfer of maternal antibiotics to breast milk, its clinical significance, and ways to minimise inadvertent infant exposure.

Drug use in first pregnancy and lactation: a population-based survey among Danish women

Olesen C, Steffensen F, Nielsen G et al., European Journal of Clinical Pharmacology (1999)
OBJECTIVE: To examine the drug prescription pattern in Danish women from 12 weeks prior to conception until 12 weeks post-partum. The post-partum prescription proportion was 34.0% and the majority of the prescriptions during this period were for penicillins (20.1%), ophthalmologicals (15.5%) and corticosteroids for dermatological use (5.7%).

Antibiotics and Breastfeeding

De Sá Del Fiol F, Barberato-Filho S, De Cássia Bergamaschi C et al. 2016
During the breastfeeding period, bacterial infections can occur in the nursing mother, requiring the use of antibiotics. A lack of accurate information may lead health care professionals and mothers to suspend breastfeeding, which may be unnecessary. This article provides information on the main antibiotics that are appropriate for clinical use and the interference of these antibiotics with the infant to support medical decisions regarding the discontinuation of breastfeeding.

Exploring the contribution of maternal antibiotics and breastfeeding to development of the infant microbiome and pediatric obesity

Lemas D, Yee S, Cacho N et al. 2016
Pediatric obesity, a significant public health concern, has been associated with adult premature mortality and the development of type 2 diabetes and cardiovascular disease. Evidence has suggested that the gut microbiota is associated with pediatric obesity. Establishment of the infant gut microbiome is dependent on a dynamic maternal???infant microbiota exchange during early life. The objective of this review is to describe maternal factors such as feeding practices and antibiotic use that may influence the infant gut microbiome and risk for obesity